Pub. Date : 2013 Dec 6
PMID : 24103391
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RATIONALE: Increased arginine-vasopressin (AVP) secretion is a key physiological response to hyperosmotic stress and may be part of the mechanism by which high-salt diets induce or exacerbate hypertension. | Salts | arginine vasopressin | Rattus norvegicus |
2 | RATIONALE: Increased arginine-vasopressin (AVP) secretion is a key physiological response to hyperosmotic stress and may be part of the mechanism by which high-salt diets induce or exacerbate hypertension. | Salts | arginine vasopressin | Rattus norvegicus |
3 | OBJECTIVE: Using deoxycorticosterone acetate-salt hypertension model rats, we sought to test the hypothesis that changes in GABA(A) receptor-mediated inhibition in AVP-secreting magnocellular neurons contribute to the generation of Na(+)-dependent hypertension. | Salts | arginine vasopressin | Rattus norvegicus |
4 | The depolarizing GABA equilibrium potential shift in AVP-secreting neurons occurred progressively over weeks of deoxycorticosterone acetate-salt treatment along with gradual increases in plasma AVP and blood pressure. | Salts | arginine vasopressin | Rattus norvegicus |
5 | Intracerebroventricular bumetanide administration during deoxycorticosterone acetate-salt treatment hindered the development of hypertension and rise in plasma AVP level. | Salts | arginine vasopressin | Rattus norvegicus |