Title : MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth.

Pub. Date : 2013

PMID : 24098708






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth. Berberine microRNA 181a-1 Homo sapiens
2 In this study, we used microRNA microarrays to find that the expression level of miR-21-3p (previously named miR-21*) increased after berberine treatment in the HepG2 human hepatoma cell line. Berberine microRNA 181a-1 Homo sapiens
3 To predict the putative targets of miR-21-3p, we integrated the gene expression profiles of HepG2 cells after berberine treatment by comparing with a gene list generated from sequence-based microRNA target prediction software. Berberine microRNA 181a-1 Homo sapiens