Title : Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.

Pub. Date : 2013

PMID : 24098536






1 Functional Relationships(s)
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1 Interestingly, while acid ceramidase was able to protect cells expressing wild type PTEN from docetaxel, promote proliferation and xenoengraftment, acid ceramidase had no impact in cells expressing PTEN-NLS. Docetaxel N-acylsphingosine amidohydrolase 1 Homo sapiens