Title : The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

Pub. Date : 2013 Nov 21

PMID : 24095279






2 Functional Relationships(s)
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1 Here, we show that RagC/D is a key regulator of the interaction of mTORC1 with the Rag heterodimer and that, unexpectedly, RagC/D must be GDP bound for the interaction to occur. Guanosine Diphosphate Ras related GTP binding C Homo sapiens
2 Here, we show that RagC/D is a key regulator of the interaction of mTORC1 with the Rag heterodimer and that, unexpectedly, RagC/D must be GDP bound for the interaction to occur. Guanosine Diphosphate Ras related GTP binding C Homo sapiens