Title : Conformational dynamics of a regulator of G-protein signaling protein reveals a mechanism of allosteric inhibition by a small molecule.

Pub. Date : 2013 Dec 20

PMID : 24093330






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 RGS proteins directly bind to the Galpha-subunits of activated heterotrimeric G-proteins, and accelerate the rate of GTP hydrolysis, thereby rapidly deactivating G-proteins. Guanosine Triphosphate paired like homeodomain 2 Homo sapiens