Title : Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis.

Pub. Date : 2013 Oct 3

PMID : 24091659






2 Functional Relationships(s)
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1 Alcohol exposure enhanced acinar cell-specific production of TNFalpha, IL-6, MCP-1 and IL-10, as early as 3 h after LPS, whereas IL-18 and caspase-1 were evident 24 h later. Alcohols tumor necrosis factor Homo sapiens
2 Alcohol enhanced LPS-induced TNFalpha expression, whereas blockade of LPS signaling diminished TNFalpha production in vitro, indicating that the response of pancreatic acinar cells to LPS is similar to that of immune cells. Alcohols tumor necrosis factor Homo sapiens