Title : Isoflavones derived from soy beans prevent MuRF1-mediated muscle atrophy in C2C12 myotubes through SIRT1 activation.

Pub. Date : 2013

PMID : 24064732






2 Functional Relationships(s)
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1 Here we report on the inhibitory effects of isoflavones such as genistein and daidzein on muscle atrophy caused by tumor necrosis factor (TNF)-alpha treatment. Isoflavones tumor necrosis factor Homo sapiens
2 Moreover, isoflavones significantly suppressed MuRF1 promoter activity and myotube atrophy induced by TNF-alpha in C2C12 myotubes. Isoflavones tumor necrosis factor Homo sapiens