Title : A neuroinformatics study describing molecular interaction of Cisplatin with acetylcholinesterase: a plausible cause for anticancer drug induced neurotoxicity.

Pub. Date : 2014 Mar

PMID : 24059317






1 Functional Relationships(s)
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1 During "Cisplatin-CAS site of AChE enzyme" interaction, it was found that out of the three amino acids constituting the catalytic triad (S203, H447 and E334), two amino acid residues namely S203 and H447 interact with Cisplatin by hydrogen bonding and hydrophobic interaction, respectively. Calcium acetylcholinesterase (Cartwright blood group) Homo sapiens