Title : Are 8-oxoguanine (8-oxoGua) and 5-hydroxymethyluracil (5-hmUra) oxidatively damaged DNA bases or transcription (epigenetic) marks?

Pub. Date : 2014 Apr

PMID : 24055867






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This involves overexpression of activation-induced cytidine deaminase (AID) and ten-eleven translocation 1 (TET1) protein (the key proteins involved in active demethylation), which leads to global accumulation of 5-hmUra. 5-hydroxymethyluracil activation induced cytidine deaminase Sus scrofa
2 This involves overexpression of activation-induced cytidine deaminase (AID) and ten-eleven translocation 1 (TET1) protein (the key proteins involved in active demethylation), which leads to global accumulation of 5-hmUra. 5-hydroxymethyluracil activation induced cytidine deaminase Sus scrofa