Title : Synergistic anti-proliferative effect of resveratrol and etoposide on human hepatocellular and colon cancer cell lines.

Pub. Date : 2013 Oct 15

PMID : 24055188






5 Functional Relationships(s)
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1 The ability of resveratrol to enhance anti-proliferative effects of etoposide in wild type p53 liver carcinoma (HepG2) and colon cancer (HCT-116) cells was investigated with focusing on p53 activation. Resveratrol tumor protein p53 Homo sapiens
2 P53 expression was up-regulated by resveratrol and etoposide and pre-incubation of both cells with resveratrol increased levels of etoposide-induced p53 expression. Resveratrol tumor protein p53 Homo sapiens
3 P53 expression was up-regulated by resveratrol and etoposide and pre-incubation of both cells with resveratrol increased levels of etoposide-induced p53 expression. Resveratrol tumor protein p53 Homo sapiens
4 P53 expression was up-regulated by resveratrol and etoposide and pre-incubation of both cells with resveratrol increased levels of etoposide-induced p53 expression. Resveratrol tumor protein p53 Homo sapiens
5 It seems that resveratrol exerts differential synergistic effect with etoposide on proliferation of cancer cells from different origin which is mainly accompanied by p53 activation. Resveratrol tumor protein p53 Homo sapiens