Title : Blockade of reactive oxygen species and Akt activation is critical for anti-inflammation and growth inhibition of metformin in phosphatase and tensin homolog-deficient RAW264.7 cells.

Pub. Date : 2013 Dec

PMID : 24053326






2 Functional Relationships(s)
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1 Blockade of reactive oxygen species and Akt activation is critical for anti-inflammation and growth inhibition of metformin in phosphatase and tensin homolog-deficient RAW264.7 cells. Metformin thymoma viral proto-oncogene 1 Mus musculus
2 Moreover, metformin affected PTEN-deficient cells dependent of inhibition of ROS production and Akt activation against enlarged inflammatory mediators and/or cell growth in shPTEN cells. Metformin thymoma viral proto-oncogene 1 Mus musculus