Title : Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3.

Pub. Date : 2013 Sep 26

PMID : 24040942






3 Functional Relationships(s)
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Protein Name
Organism
1 Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3. N(2)-methyl-L-lysine L3MBTL histone methyl-lysine binding protein 3 Homo sapiens
2 We previously reported the discovery of 1 (UNC1215), the first potent and selective small-molecule chemical probe of a methyl-lysine reader protein, L3MBTL3, which antagonizes the mono- and dimethyl-lysine reading function of L3MBTL3. N(2)-methyl-L-lysine L3MBTL histone methyl-lysine binding protein 3 Homo sapiens
3 We previously reported the discovery of 1 (UNC1215), the first potent and selective small-molecule chemical probe of a methyl-lysine reader protein, L3MBTL3, which antagonizes the mono- and dimethyl-lysine reading function of L3MBTL3. N(2)-methyl-L-lysine L3MBTL histone methyl-lysine binding protein 3 Homo sapiens