Title : Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway.

Pub. Date : 2014 Jun

PMID : 24038588






1 Functional Relationships(s)
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1 The results showed that the JAK/STAT pathway activation by proinflammatory cytokine interleukin-6 and interferon-gamma in CCA cells was suppressed by pretreatment with quercetin and EGCG, evidently by a decrease of the elevated phosphorylated-STAT1 and STAT3 proteins in a dose-dependent manner. epigallocatechin gallate signal transducer and activator of transcription 1 Homo sapiens