Title : Promoter deletions of Klebsiella pneumoniae carbapenemase (KPC)-encoding genes (blaKPC -2) and efflux pump (AcrAB) on β-lactam susceptibility in KPC-producing Enterobacteriaceae.

Pub. Date : 2013 Nov

PMID : 24033858






1 Functional Relationships(s)
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1 To better understand the variability in beta-lactam MICs among KPC-producing Enterobacteriaceae, three isoforms of bla(KPC-2) gene were used to transform Escherichia coli W4573 and its deletion mutant of an efflux pump (AcrAB) to examine the effects on beta-lactam susceptibility. beta-Lactams KPC-2 Escherichia coli