Pub. Date : 2014 Feb
PMID : 24030355
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sodium fluoride disrupts DNA methylation of H19 and Peg3 imprinted genes during the early development of mouse embryo. | Sodium Fluoride | paternally expressed 3 | Mus musculus |
| 2 | Data indicate that H19, a paternally imprinted gene, compared to control embryos, was less methylated in 8-cell embryos from pregnant mice treated with NaF (100 mg/l) in drinking water for 48 h. Peg3, a maternally imprinted gene, and the Line1 repeated sequence were similarly methylated in NaF-treated and control embryos. | Sodium Fluoride | paternally expressed 3 | Mus musculus |
| 3 | Data indicate that H19, a paternally imprinted gene, compared to control embryos, was less methylated in 8-cell embryos from pregnant mice treated with NaF (100 mg/l) in drinking water for 48 h. Peg3, a maternally imprinted gene, and the Line1 repeated sequence were similarly methylated in NaF-treated and control embryos. | Sodium Fluoride | paternally expressed 3 | Mus musculus |
| 4 | Female mice mated with NaF-treated male mice (35 days) had less methylated H19, but Peg3 was significantly more methylated. | Sodium Fluoride | paternally expressed 3 | Mus musculus |