Title : The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse.

Pub. Date : 2013 Nov 15

PMID : 24008358






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1 The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse. Ceruletide cystathionase (cystathionine gamma-lyase) Mus musculus
2 In this study, we sought to determine whether endogenously synthesized H2S via cystathionine-gamma-lyase (CSE) plays a pro- or anti-inflammatory role in caerulein-induced pancreatitis. Ceruletide cystathionase (cystathionine gamma-lyase) Mus musculus
3 In this study, we sought to determine whether endogenously synthesized H2S via cystathionine-gamma-lyase (CSE) plays a pro- or anti-inflammatory role in caerulein-induced pancreatitis. Ceruletide cystathionase (cystathionine gamma-lyase) Mus musculus
4 To investigate this, we used mice genetically deficient in CSE to elucidate the function of CSE in caerulein-induced acute pancreatitis. Ceruletide cystathionase (cystathionine gamma-lyase) Mus musculus
5 Additionally, in WT mice, there was a greater level of pancreatic CSE expression and sulfide-synthesizing activity in caerulein-induced pancreatitis compared with the saline control. Ceruletide cystathionase (cystathionine gamma-lyase) Mus musculus