Pub. Date : 2013 Oct 15
PMID : 23997174
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated the effects of fluticasone on transforming growth factor (TGF)-beta- and cigarette smoke-induced changes in mothers against decapentaplegic homolog (Smad) signaling and extracellular matrix (ECM) production in airway and parenchymal lung fibroblasts from patients with severe COPD. | Fluticasone | transforming growth factor beta 1 | Homo sapiens |
| 2 | We showed that TGF-beta-induced ECM production by pulmonary fibroblasts, but not activation of the Smad pathway, was sensitive to the effects of fluticasone. | Fluticasone | transforming growth factor beta 1 | Homo sapiens |
| 3 | Fluticasone induced decorin production by airway fibroblasts and partly reversed the negative effects of TGF-beta treatment. | Fluticasone | transforming growth factor beta 1 | Homo sapiens |