Title : LKB1/AMPK/mTOR signaling pathway in non-small-cell lung cancer.

Pub. Date : 2013

PMID : 23991948






2 Functional Relationships(s)
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1 Besides the discovery of somatic mutations in the LKB1 gene in certain type of cancers, a critical emerging point was that the LKB1/AMPK axis remains generally functional and could be stimulated by pharmacological molecules such as metformin in cancer cells. Metformin serine/threonine kinase 11 Homo sapiens
2 Besides the discovery of somatic mutations in the LKB1 gene in certain type of cancers, a critical emerging point was that the LKB1/AMPK axis remains generally functional and could be stimulated by pharmacological molecules such as metformin in cancer cells. Metformin serine/threonine kinase 11 Homo sapiens