Title : Effects of triclabendazole on secretion of danofloxacin and moxidectin into the milk of sheep: role of triclabendazole metabolites as inhibitors of the ruminant ABCG2 transporter.

Pub. Date : 2013 Nov

PMID : 23981352






1 Functional Relationships(s)
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Protein Name
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1 TCBZSO and TCBZSO2 inhibited ruminant ABCG2 in vitro by reversing the reduced mitoxantrone accumulation and reducing basal to apical transport of nitrofurantoin in cells transduced with bovine variants (S581 and Y581) and the ovine variant of ABCG2. tcbzso2 ATP binding cassette subfamily G member 2 Bos taurus