Title : Store-operated Ca2+ channels blockers inhibit lipopolysaccharide induced astrocyte activation.

Pub. Date : 2013 Oct

PMID : 23974726






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1 Using calcium imaging technology, we first found that SOC channels blockers, 1-[h-[3-(4-methoxyphenyl)propoxy]-4-methoxyphenethyl]-1H-imidazole (SKF-96365) and 2-aminoethyldiphenyl borate (2-APB), inhibited LPS induced [Ca(2+)]i increase, which prompted us to speculate that SOC channels may be involved in LPS induced astrocyte activation. Calcium arginyl aminopeptidase Homo sapiens