Title : Precision 're'arming of CD33 antibodies.

Pub. Date : 2013 Aug 22

PMID : 23970353






2 Functional Relationships(s)
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1 In this issue of Blood, Kung Sutherland et al report on the preclinical activity of SGN-CD33A, a humanized anti-CD33 antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a protease-cleavable linker, against acute myeloid leukemia (AML) cells in vitro and in vivo. pyrrolo(2,1-c)(1,4)benzodiazepine CD33 molecule Homo sapiens
2 In this issue of Blood, Kung Sutherland et al report on the preclinical activity of SGN-CD33A, a humanized anti-CD33 antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a protease-cleavable linker, against acute myeloid leukemia (AML) cells in vitro and in vivo. pyrrolo(2,1-c)(1,4)benzodiazepine CD33 molecule Homo sapiens