Pub. Date : 2013 Oct
PMID : 23966322
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Normal pregnancy is supported by increased levels of progesterone (P4), which is secreted from ovarian luteal cells via enzymatic steps catalyzed by P450scc (CYP11A1) and HSD3B. | Progesterone | cytochrome P450, family 11, subfamily a, polypeptide 1 | Mus musculus |
| 2 | Normal pregnancy is supported by increased levels of progesterone (P4), which is secreted from ovarian luteal cells via enzymatic steps catalyzed by P450scc (CYP11A1) and HSD3B. | Progesterone | cytochrome P450, family 11, subfamily a, polypeptide 1 | Mus musculus |
| 3 | Thus, overexpression of Cyp11a1 disrupts normal development of the corpus luteum, leading to progesterone insufficiency during early pregnancy. | Progesterone | cytochrome P450, family 11, subfamily a, polypeptide 1 | Mus musculus |