Title : Signaling pathways involved in 1-octen-3-ol-mediated neurotoxicity in Drosophila melanogaster: implication in Parkinson’s disease.

Pub. Date : 2014 Feb

PMID : 23959949






2 Functional Relationships(s)
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1 Using our in vivo Drosophila system, the modulatory roles of important signaling pathways:JNK, Akt and the caspase-3-dependent apoptotic pathway were investigated in the context of 1-octen-3-ol-induced dopamine neurotoxicity. 1-octen-3-ol basket Drosophila melanogaster
2 Thus, we found that Akt and JNK both protect against loss of dopamine activity associated with 1-octen-3-ol exposure, indicating the pro-survival role of these signaling pathways. 1-octen-3-ol basket Drosophila melanogaster