Title : Reactive oxygen species play a central role in hexavalent chromium-induced apoptosis in Hep3B cells without the functional roles of p53 and caspase-3.

Pub. Date : 2013

PMID : 23942225






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1 METHODS: In the present study, by using Z-VAD-fmk to inhibit caspase-3 in p53-deficient Hep3B cells, we explored the effect of Cr(VI) on apoptosis induction and the related mechanisms when the functions of p53 and caspase were simultaneously blocked. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 3 Homo sapiens