Title : Variation in IFNL4 genotype and response to interferon-based therapy of hepatitis C in HIV-positive patients with acute and chronic hepatitis C.

Pub. Date : 2013 Nov 13

PMID : 23939236






1 Functional Relationships(s)
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1 Analysing 206 HCV(+)/HIV(+) and 162 HCV(+)/HIV(-) patients, we found that compared with IL28B rs12979860, IFNL4 ss469415590 was strongly associated with response to interferon/ribavirin therapy in HCV(+)/HIV(-) individuals but not in HIV(+)/HCV(+) patients. Ribavirin interferon lambda 4 (gene/pseudogene) Homo sapiens