Title : Group A streptococci are protected from amoxicillin-mediated killing by vesicles containing β-lactamase derived from Haemophilus influenzae.

Pub. Date : 2014 Jan

PMID : 23912886






4 Functional Relationships(s)
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1 Group A streptococci are protected from amoxicillin-mediated killing by vesicles containing beta-lactamase derived from Haemophilus influenzae. Amoxicillin beta-lactamase TEM-1 Haemophilus influenzae
2 The hydrolysis of amoxicillin by beta-lactamase was estimated by an agar diffusion method. Amoxicillin beta-lactamase TEM-1 Haemophilus influenzae
3 RESULTS: We showed that OMVs released from beta-lactam-resistant M. catarrhalis and NTHi contain functional beta-lactamase that hydrolyses amoxicillin and protects GAS from killing by amoxicillin. Amoxicillin beta-lactamase TEM-1 Haemophilus influenzae
4 RESULTS: We showed that OMVs released from beta-lactam-resistant M. catarrhalis and NTHi contain functional beta-lactamase that hydrolyses amoxicillin and protects GAS from killing by amoxicillin. Amoxicillin beta-lactamase TEM-1 Haemophilus influenzae