Title : Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells.

Pub. Date : 2014 Jun 26

PMID : 23912457






1 Functional Relationships(s)
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1 Moreover, treatment with the MUC1-C inhibitor, GO-203, was associated with disruption of MUC1-C/HER2 complexes and decreases in tyrosine-phosphorylated HER2 (p-HER2) levels. Tyrosine mucin 1, cell surface associated Homo sapiens