Title : Design, synthesis, and mechanistic investigations of bile acid-tamoxifen conjugates for breast cancer therapy.

Pub. Date : 2013 Sep 18

PMID : 23909664






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ROS assays showed a high amount of generation of ROS independent of ER status of the cell line indicating changes in mitochondrial membrane fluidity upon the uptake of the conjugate that further leads to the release of cytochrome c, a direct and indirect regulator of ROS. ros cytochrome c, somatic Homo sapiens
2 ROS assays showed a high amount of generation of ROS independent of ER status of the cell line indicating changes in mitochondrial membrane fluidity upon the uptake of the conjugate that further leads to the release of cytochrome c, a direct and indirect regulator of ROS. ros cytochrome c, somatic Homo sapiens
3 ROS assays showed a high amount of generation of ROS independent of ER status of the cell line indicating changes in mitochondrial membrane fluidity upon the uptake of the conjugate that further leads to the release of cytochrome c, a direct and indirect regulator of ROS. ros cytochrome c, somatic Homo sapiens