Title : Flavopiridol synergizes with sorafenib to induce cytotoxicity and potentiate antitumorigenic activity in EGFR/HER-2 and mutant RAS/RAF breast cancer model systems.

Pub. Date : 2013 Aug

PMID : 23908594






2 Functional Relationships(s)
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1 Drug combination studies show that the pan-CDK inhibitor, flavopiridol (FPD), synergistically potentiated cytotoxicity induced by the Raf inhibitor, sorafenib (SFN). Sorafenib zinc fingers and homeoboxes 2 Homo sapiens
2 Drug combination studies show that the pan-CDK inhibitor, flavopiridol (FPD), synergistically potentiated cytotoxicity induced by the Raf inhibitor, sorafenib (SFN). Sorafenib zinc fingers and homeoboxes 2 Homo sapiens