Title : ML309: A potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cells

Pub. Date : 2010

PMID : 23905201






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The mutated residue in IDH1 is most commonly arginine 132, which is most often replaced with either histidine or cysteine. Histidine isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens