Title : Sulindac modulates secreted protein expression from LIM1215 colon carcinoma cells prior to apoptosis.

Pub. Date : 2013 Nov

PMID : 23899461






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Taken together these results indicate that during the early-stage onset of sulindac-induced apoptosis (evidenced by increased annexin V binding, dephosphorylation of focal adhesion kinase (FAK), and cleavage of caspase-3), 1mM sulindac treatment of LIM1215 cells results in decreased expression of secreted proteins implicated in ECM remodeling, mucosal maintenance and cell-cell-adhesion. Sulindac caspase 3 Homo sapiens