Title : Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi.

Pub. Date : 2013

PMID : 23894476






2 Functional Relationships(s)
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1 In addition, when Saccharomyces cerevisiae null mutants for this gene (PUT1) were complemented with the TcPRODH gene, diminished free intracellular proline levels and an enhanced sensitivity to oxidative stress in comparison to the null mutant were observed, supporting the hypothesis that free proline accumulation constitutes a defense against oxidative imbalance. Proline proline dehydrogenase Saccharomyces cerevisiae S288C
2 In addition, when Saccharomyces cerevisiae null mutants for this gene (PUT1) were complemented with the TcPRODH gene, diminished free intracellular proline levels and an enhanced sensitivity to oxidative stress in comparison to the null mutant were observed, supporting the hypothesis that free proline accumulation constitutes a defense against oxidative imbalance. Proline proline dehydrogenase Saccharomyces cerevisiae S288C