Title : The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway.

Pub. Date : 2013 Aug 12

PMID : 23891662






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The GDP-bound, Gbetagamma-free Galphai subunit accumulates at the front of chemotaxing neutrophils to recruit mInsc-complexed with the Par3-aPKC evolutionarily conserved polarity complex-via LGN/AGS3 that simultaneously binds to Galphai-GDP and mInsc. Guanosine Diphosphate G protein signaling modulator 1 Homo sapiens