Pub. Date : 2013 Jul
PMID : 23880302
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | After the selection of the best model, a folic acid molecule was docked "in silico" onto the putative binding site and its binding mode was compared with that of vintafolide, a much larger molecule designed as a chemotherapy agent targeting specifically FRalpha. | Folic Acid | rabaptin, RAB GTPase binding effector protein 2 | Homo sapiens |
2 | In both cases, a 40ns molecular dynamics trajectory was calculated, providing suggestions regarding the key structural determinants driving the affinity and specificity of FRalpha for folic acid with respect to other folate homologues. | Folic Acid | rabaptin, RAB GTPase binding effector protein 2 | Homo sapiens |
3 | In both cases, a 40ns molecular dynamics trajectory was calculated, providing suggestions regarding the key structural determinants driving the affinity and specificity of FRalpha for folic acid with respect to other folate homologues. | Folic Acid | rabaptin, RAB GTPase binding effector protein 2 | Homo sapiens |