Title : Increase in antinociceptive effect of [leu5]enkephalin after intrathecal administration of mixture of three peptidase inhibitors.

Pub. Date : 2013 Jul 20

PMID : 23868737






1 Functional Relationships(s)
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1 OBJECTIVE: Previous in vitro studies have shown that the degradation of [Leu5]enkephalin during incubation with cerebral membrane preparations is almost completely prevented by a mixture of three peptidase inhibitors such as amastatin, captopril, and phosphoramidon. phosphoramidon proenkephalin Rattus norvegicus