Title : Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors.

Pub. Date : 2013 Jul 22

PMID : 23864426






1 Functional Relationships(s)
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1 A novel approach--replacing galactose with its C2 epimer, talose--offers an alternative framework, as extensions at C2 permit exploitation of a galectin-3-specific binding groove, thereby facilitating the design of selective inhibitors. Galactose lectin, galactose binding, soluble 3 Mus musculus