Title : Cys-leukotrienes promote fibrosis in a mouse model of eosinophil-mediated respiratory inflammation.

Pub. Date : 2013 Dec

PMID : 23859654






1 Functional Relationships(s)
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1 More importantly, the loss of leukotrienes led to an unexpectedly significant decrease in collagen deposition (i.e., pulmonary fibrosis) that accompanied elevated levels of IL-4/-13 and TGF-beta in the lungs of I5/hE2 mice. Leukotrienes cystatin 12, pseudogene Homo sapiens