Pub. Date : 2013 Sep
PMID : 23849427
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Asp residues of the Glu-Glu-Asp-Asp pore filter contribute to ion permeation and selectivity of the Ca(v)3.2 T-type channel. | Glutamic Acid | immunoglobulin lambda variable 7-43 | Homo sapiens |
| 2 | Asp residues of the Glu-Glu-Asp-Asp pore filter contribute to ion permeation and selectivity of the Ca(v)3.2 T-type channel. | Glutamic Acid | immunoglobulin lambda variable 7-43 | Homo sapiens |
| 3 | Electrophysiological characterization of the pore mutant channels in which the pore Asp residue(s) were replaced with Glu, showed that both Asp residues critically control the biophysical properties of Ca(v)3.2, including relative permeability between Ba2+ and Ca2+, anomalous mole fraction effect (AMFE), voltage dependency of channel activation, Cd2+ blocking sensitivity, and pH effects, in distinctive ways. | Glutamic Acid | immunoglobulin lambda variable 7-43 | Homo sapiens |