Title : Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism.

Pub. Date : 2013 Oct

PMID : 23846873






1 Functional Relationships(s)
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1 The aryl hydrocarbon receptor (AHR)-dependent induction of cytochromes P450 (P450) such as CYP1A1 by 3-methylcholanthrene (MC) and related polycyclic aromatic hydrocarbons is well characterized. Polycyclic Aromatic Hydrocarbons cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus