Title : Effect of apoA-I Mutations in the Capacity of Reconstituted HDL to Promote ABCG1-Mediated Cholesterol Efflux.

Pub. Date : 2013

PMID : 23826352






1 Functional Relationships(s)
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1 Further analysis showed that rHDL containing the carboxyl-terminal deletion mutant apoA-I[Delta(185-243)] only slightly reduced (by 22%) the ABCG1-mediated efflux of 7-ketocholesterol, indicating that depending on the sterol type, structural changes in rHDL-associated apoA-I affect differently the ABCG1-mediated efflux of cholesterol and 7-ketocholesterol. 7-ketocholesterol ATP binding cassette subfamily G member 1 Homo sapiens