Title : Prostaglandin F2α upregulates Slit/Robo expression in mouse corpus luteum during luteolysis.

Pub. Date : 2013 Sep

PMID : 23814012






1 Functional Relationships(s)
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1 Both in vitro and in vivo studies showed that PGF2 alpha significantly increases the expression of Slit2 and Robo1 during luteolysis through protein kinase C-dependent ERK1/2 and P38 MAPK signaling pathways, whereas an inhibitor of Slit/Robo signaling significantly decreases the stimulating effect of PGF2 alpha on luteolysis. Dinoprost mitogen-activated protein kinase 3 Mus musculus