Title : Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions.

Pub. Date : 2013 Sep 1

PMID : 23813959






1 Functional Relationships(s)
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1 We validated a subset of the predictions using qRT-PCR, luciferase reporter assays and western blotting, including the known interaction between miR-200 and ZEB2 (involved in epithelial-mesenchymal transition) and the novel interaction between miR-200 and SOX17 (a key transcription factor in specification of definitive endoderm). mir-200 zinc finger E-box binding homeobox 2 Homo sapiens