Title : Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models.

Pub. Date : 2014 May 22

PMID : 23812423






1 Functional Relationships(s)
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1 Capitalizing on the growing importance and relevance of zebrafish (Danio rerio) as an alternate cancer model, we have generated liver-specific, Tet-on-inducible transgenic lines expressing oncogenic Kras(G12V), RhoA, constitutively active RhoA(G14V) or dominant-negative RhoA(T19N). tetramethylenedisulfotetramine ras homolog gene family, member Ab Danio rerio