Title : A novel upregulation of glutathione peroxidase 1 by knockout of liver-regenerating protein Reg3β aggravates acetaminophen-induced hepatic protein nitration.

Pub. Date : 2013 Dec

PMID : 23811004






1 Functional Relationships(s)
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1 Their elevated protein nitration was alleviated by a prior injection of recombinant mouse Reg3beta protein and was associated with an accelerated depletion of the peroxynitrite (ONOO(-)) scavenger glutathione by an upregulated hepatic glutathione peroxidase-1 (GPX1) activity. Peroxynitrous Acid regenerating islet-derived 3 beta Mus musculus