Title : Anti-inflammatory effect of tetrahydrocoptisine from Corydalis impatiens is a function of possible inhibition of TNF-α, IL-6 and NO production in lipopolysaccharide-stimulated peritoneal macrophages through inhibiting NF-κB activation and MAPK pathway.

Pub. Date : 2013 Sep 5

PMID : 23810685






1 Functional Relationships(s)
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1 Taken together, our data suggest that THC is an active anti-inflammatory constituent by inhibition of TNF-alpha, IL-6 and NO production possibly via down-regulation of NF-kappaB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways. stylopine mitogen-activated protein kinase 3 Mus musculus