Title : p53 expression in pretreatment specimen predicts response to neoadjuvant chemotherapy including anthracycline and taxane in patients with primary breast cancer.

Pub. Date : 2013

PMID : 23804139






3 Functional Relationships(s)
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1 In a comparison between the 9 (5%) sensitive patients and 30 (16%) insensitive patients, overexpression of p53 but not overexpression of either HER2 or EGFR was associated with a good response to NAC. nac tumor protein p53 Homo sapiens
2 p53 (p=0.045) and histological grade 3 (p=0.011) were important and significant predictors of the response to NAC. nac tumor protein p53 Homo sapiens
3 We conclude that the level of p53 expression in the CNB was an effective and reliable predictor of treatment response to NAC. nac tumor protein p53 Homo sapiens