Title : Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice.

Pub. Date : 2013 Aug 15

PMID : 23792144






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1 Our data showed that neferine significantly restored the significant reductions in body weights, the increased levels of lung index and hydroxyproline, the abnormal histological findings, the serum SP-D increase, the Th1/Th2 imbalance by decreasing IL-4 and increasing IFN-gamma levels and the increases in the population of CD4+CD25+ Tregs associated with amiodarone instillation in mice. neferine interleukin 4 Mus musculus