Pub. Date : 2013 Sep
PMID : 23775496
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Hydrogen peroxide-resistant and castration-resistant cells that overexpressed Twist1 and Y-box binding protein-1 (YB-1) were cross-resistant to cytotoxic agents, including docetaxel. | Docetaxel | Y-box binding protein 1 | Homo sapiens |
| 2 | RESULTS: Hydrogen peroxide-resistant and castration-resistant cells that overexpressed Twist1 and Y-box binding protein-1 (YB-1) were cross-resistant to cytotoxic agents, including docetaxel. | Docetaxel | Y-box binding protein 1 | Homo sapiens |
| 3 | Twist1 and/or YB-1 were activated in docetaxel-resistant prostate cancer cells, and YB-1 was activated by docetaxel treatment. | Docetaxel | Y-box binding protein 1 | Homo sapiens |
| 4 | Twist1 and/or YB-1 were activated in docetaxel-resistant prostate cancer cells, and YB-1 was activated by docetaxel treatment. | Docetaxel | Y-box binding protein 1 | Homo sapiens |
| 5 | Conversely, Twist1 and YB-1 knockdown sensitized prostate cancer cells to cytotoxic agents, including docetaxel. | Docetaxel | Y-box binding protein 1 | Homo sapiens |
| 6 | CONCLUSIONS: Twist1/YB-1 and AR signaling promote docetaxel resistance in CRPC cells. | Docetaxel | Y-box binding protein 1 | Homo sapiens |