Title : Neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson's-like disease: possible role of SOCS-1 in reducing pro-inflammatory responses.

Pub. Date : 2014 Apr

PMID : 23764428






1 Functional Relationships(s)
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1 We observed that resveratrol treatment significantly reduced glial activation, decreasing the levels of IL-1beta, IL-6 and TNF-alpha, as well as their respective receptors in the SNpc of MPTP-treated mice, as demonstrated by Western blotting, RT-PCR and quantitative PCR analysis. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine interleukin 1 beta Mus musculus