Title : Sertoli cell is a potential target for perfluorooctane sulfonate-induced reproductive dysfunction in male mice.

Pub. Date : 2013 Sep

PMID : 23761298






2 Functional Relationships(s)
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1 Additionally, PFOS decreased the expression of junction proteins in Sertoli cells, which was further confirmed by in vivo results that PFOS decreased or dislocated junction proteins (i.e., ZO-1, occludin, claudin-11, and connexin-43) and increased proteins related to the MAPK signaling pathway (i.e., Erk and p38), whereas basal ectoplasmic specialization proteins did not change. perfluorooctane sulfonic acid mitogen-activated protein kinase 14 Mus musculus
2 Additionally, PFOS decreased the expression of junction proteins in Sertoli cells, which was further confirmed by in vivo results that PFOS decreased or dislocated junction proteins (i.e., ZO-1, occludin, claudin-11, and connexin-43) and increased proteins related to the MAPK signaling pathway (i.e., Erk and p38), whereas basal ectoplasmic specialization proteins did not change. perfluorooctane sulfonic acid mitogen-activated protein kinase 14 Mus musculus